Injectable hyaluronic acid composite hydrogel with nano calcium phosphate via in-situ precipitation for dermal filler applications
نویسندگان
چکیده
منابع مشابه
Abstract: The Next-Generation Dermal Filler: Nanofiber-Hydrogel Composite
INTRODUCTION: Soft tissue losses from aging, trauma, or congenital malformation affect millions of people each year. Injectable fillers are effective in providing soft tissue volumization for facial rejuvenation and reconstruction. The majority of dermal fillers are based on hyaluronic acid (HA) and rely on high concentrations of HA to provide adequate viscosity and temporary persistence. This ...
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In this study, L-lactide was used to modify the tricalcium phosphate (β-TCP) and tetracalcium phosphate (TTCP) surface which can form functionalized poly(l-lactic acid) (PLLA)-grafted β-TCP (g-β-TCP) and PLLA-grafted TTCP (g-TTCP) particles. The g-β-TCP and g-TTCP obtained were incorporated into a PEG-PCL-PEG (PECE) matrix to prepare injectable thermosensitive hydrogel composites. The morpholog...
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BACKGROUND Osteoarthritis (OA) is a common joint disease that causes disabilities in elderly adults. However, few long-lasting pharmacotherapeutic agents with low side effects have been developed to treat OA. We evaluated the therapeutic effects of intra-articular injections of hydrogels containing hyaluronic acid (HA) and doxycycline (DOX) in a rabbit OA model. RESULTS Thirteen week old New ...
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BACKGROUND Dermal gel extra (DGE) is a new, tightly cross-linked hyaluronic acid (HA)-based dermal filler containing lidocaine engineered to resist gel deformation and degradation. OBJECTIVES To develop a firmer gel product (DGE) and compare the efficacy and safety of DGE with nonanimal stabilized HA (NASHA) for correction of nasolabial folds (NLFs). METHODS DGE physical properties were cha...
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ژورنال
عنوان ژورنال: Frontiers in Bioengineering and Biotechnology
سال: 2016
ISSN: 2296-4185
DOI: 10.3389/conf.fbioe.2016.01.01907